About
Research interests
- High throughput proteomics analysis of cell signaling
- Elucidation of artificial microstructures and nanoparticles on cell functioning
- Studies of RAS-dependent signaling pathways in various cell culture models
Main Grants
Projects
- Research Council of Lithuania. High throughput proteomics for cancer cell surface protein recognition by quantum dots. Dr. M. Valius, 2014–2016.
- Agency for Science, Innovation and Technology. Creation of biologically active regular three-dimensional structures for tissue molecular bioengineering, Dr. M. Valius, 2012-2013
- Participation in Global grant „Molecular mechanisms of the toxicity and antitumour activity of quinones and polyphenols: enzymatic redox reactions, cytotoxicity, signal transduction and proteomics “, Habil. Dr. N. Čenas (Dept. Xenobiotics Biochemistry), 2011-2015
- Participation in the project supported by the European Social Fund under National Integrated Programme. Biotechnology and Biopharmacy: fundamental and applied research, 2012-2015. Action 1.1.3. Molecular processes in eukaryotic cells: the technological and medical aspects. Head of Action Prof. Dr. R. Navakauskienė (Dept. Mol. Cell Biology).
Main publications
2019
1. Balčiūnas, E., Baldock, S.J., Dreižė, N., Grubliauskaitė, M., Coultas, S., Rochester, D.L., Valius, M., Hardy, J.G. and Baltriukienė, D., 2019. 3D Printing Hybrid Organometallic Polymer‐Based Biomaterials via Laser Two‐Photon Polymerisation. Polymer International. IF 2.433
2. Kuciauskas, D., Dreize, N., Ger, M., Kaupinis, A., Zemaitis, K., Stankevicius, V., Suziedelis, K., Cicenas, J., Graves, L.M. and Valius, M., 2019. Proteomic Analysis of Breast Cancer Resistance to the Anticancer Drug RH1 Reveals the Importance of Cancer Stem Cells. Cancers, 11(7), p.972. IF 6.162
3. Peterman, E., Gibieža, P., Schafer, J., Skeberdis, V.A., Kaupinis, A., Valius, M., Heiligenstein, X., Hurbain, I., Raposo, G. and Prekeris, R., 2019. The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation. Nature communications, 10(1), pp.1-16. IF 11.878
4. Rynkeviciene, R., Simiene, J., Strainiene, E., Stankevicius, V., Usinskiene, J., Miseikyte Kaubriene, E., Meskinyte, I., Cicenas, J. and Suziedelis, K., 2019. Non-coding RNAs in glioma. Cancers, 11(1), p.17. IF 6.162
5. Šimoliūnas, E., Truncaitė, L., Rutkienė, R., Povilonienė, S., Goda, K., Kaupinis, A., Valius, M. and Meškys, R., 2019. The robust self-assembling tubular nanostructures formed by gp053 from phage vB_EcoM_FV3. Viruses, 11(1), p.50. IF 3.811
6. Umbrasas, D., Jokubka, R., Kaupinis, A., Valius, M., Arandarčikaitė, O. and Borutaitė, V., 2019. Nitric Oxide Donor NOC-18-Induced Changes of Mitochondrial Phosphoproteome in Rat Cardiac Ischemia Model. Medicina, 55(10), p.631. IF 1.467
7. Vaičikauskaitė, M., Ger, M., Valius, M., Maneikis, A., Lastauskienė, E., Kalėdienė, L. and Kaunietis, A., 2019. Geobacillin 26-high molecular weight bacteriocin from a thermophilic bacterium. International journal of biological macromolecules, 141, pp.333-344. IF 4.784
8. Vitkevičienė, A., Janulis, V., Žučenka, A., Borutinskaitė, V., Kaupinis, A., Valius, M., Griškevičius, L. and Navakauskienė, R., 2019. Oxidative phosphorylation inhibition induces anticancerous changes in therapy‐resistant–acute myeloid leukemia patient cells. Molecular carcinogenesis. IF 3.411
2018
Korabliovienė, J., Mauricas, M., Ambrozevičienė, Č., Valius, M., Kaupinis, A., Čaplinskas, S. and Korabliov, P., 2018. Mycobacteria produce proteins involved in biofilm formation and growth-affecting processes. Acta microbiologica et immunologica Hungarica, 65(3), pp.405-418.
GER, M., KAUPINIS, A., PETRULIONIS, M., KURLINKUS, B., CICENAS, J., SILEIKIS, A., VALIUS, M. and STRUPAS, K., 2018. Proteomic Identification of FLT3 and PCBP3 as Potential Prognostic Biomarkers for Pancreatic Cancer. Anticancer research, 38(10), pp.5759-5765.
Cicenas, J., Zalyte, E., Rimkus, A., Dapkus, D., Noreika, R. and Urbonavicius, S., 2018. JNK, p38, ERK, and SGK1 inhibitors in cancer.
Cicenas, J., Zalyte, E., Bairoch, A. and Gaudet, P., 2018. Kinases and Cancer.
Bikulčius, G., Češūnienė, A., Selskienė, A., Grigucevičienė, A., Jasulaitienė, V. and Ger, M., 2018. Characterization of Cr–ZrO2 composite coatings electrodeposited from Cr (III) bath. Chemija, 29(2).
2017
Gupta, P.P., Bastikar, V.A., Kuciauskas, D., Kothari, S.L., Cicenas, J. and Valius, M., 2017. Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1. Medical Oncology, 34(10), p.176.
2016
Ger, M., Kaupinis, A., Nemeikaite-Ceniene, A., Sarlauskas, J., Cicenas, J., Cenas, N. and Valius, M., 2016. Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1864(2), pp.219-232.
2014
Cicenas, J., Kalyan, K., Sorokinas, A., Jatulyte, A., Valiunas, D., Kaupinis, A. and Valius, M., 2014. Highlights of the latest advances in research on CDK inhibitors. Cancers, 6(4), pp.2224-2242.
Karabanovas, V., Zitkus, Z., Kuciauskas, D., Rotomskis, R. and Valius, M., 2014. Surface properties of quantum dots define their cellular endocytic routes, mitogenic stimulation and suppression of cell migration. Journal of biomedical nanotechnology, 10(5), pp.775-786.
Personnel
Head of department
Dr. Mindaugas Valius
Senior research fellow
8 522 34410
Research staff
Dr. Jonas Cicėnas senior research fellow 8 522 38220 |
Dr. Algirdas Kaupinis research fellow 8 522 34411 |
Dr. Marija Ger research fellow 8 522 34411 |
Nadežda Dreižė junior research fellow 8 522 34415 |
PhD students
Giedrė Karzaitė | Silvija Urnikytė |
Eglė Žalytė |
Tatjana Akopova | Ingrida Meškinytė |
Technical staff
Tatjana Akropova technician |